Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorHeart and Brain Research Group, Germany

About this trial

Postoperative delirium (POD) and postoperative cognitive decline (POCD) can be observed after cardiosurgical interventions. Taken together, these postoperative neurocognitive dysfunctions contribute to increased morbidity and mortality and higher economic costs. Preoperative risk factors of postoperative neurocognitive dysfunctions, such as decreased neuropsychometric performance or decreased cognitive daily activities, can be interpreted as reduced cognitive reserve. The aim of this study is to build up cognitive reserves to protect against the development of POD and POCD through preoperative, home-based, cognitive training.

Eligibility criteria

Qualifiers

Elective cardiac surgery (coronary artery bypass surgery, aortic or mitral valve replacement/reconstruction, or combination surgery) with standardized extracorporeal circulation

A sufficiently good knowledge of German is necessary as cognitive training and neuropsychological tests are language-dependent

Disqualifiers

History of stroke and preexisting psychiatric or neurological disorders that may impair the neuropsychological performance

Trial design

Treatments tested in this trial

  • Cognitive training

Treatment groups

100 Participants
are divided into 2 treatment groups