Increasing Smoking Cessation Success Through Sleep-amplified Memory Consolidation

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorCentral Institute of Mental Health, Mannheim

About this trial

The goal of this subproject is to examine the hypothesized improvement of treatment with chess-based training and sleep enhancement, both together and on their own, in smokers.

Participants will undergo fMRI measurements, sleep monitoring. They will then be assigned to one of the four experimental groups, including high-intensity interval training with or without chess-based training.

Eligibility criteria

Qualifiers

severe tobacco use disorder (TUD) according to DSM-5

sufficient ability to communicate with investigators and answer questions in both written and verbal format

ability to provide fully informed consent and to use self-rating scales

right-handedness

Disqualifiers

severe internal, neurological, and/or psychiatric comorbidities; other Axis I mental disorders other than TUD according to ICD-10 and DSM 5 (except for mild depression, i.e. F32.0, adjustment disorder and specific phobias) in the last 12 months

history of brain injury

severe physical diseases

common exclusion criteria for MRI (e.g. metal, claustrophobia)

Trial design

Treatments tested in this trial

  • Standard smoking cessation program (SCP)
  • Cognitive remediation treatment (CRT)
  • High-intensity interval training (HIIT evening)

Treatment groups

140 Participants
are divided into 4 treatment groups