Individual Risk Profiles for Adverse Drug Reactions in Geriatric Patients

ConditionsPolypharmacy Pharmacogenetics Pharmacogenomic Testing Drug-Related Side Effects and Adverse Reactions

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age70+

SponsorRWTH Aachen University

About this trial

This project will generate a prospective cohort of geriatric patients with polypharmacy which will be characterized for vulnerability profiles of adverse drug reactions.

Eligibility criteria

Qualifiers

70 years or older

Current drug therapy with three or more drugs

Being a patient in the interdisciplinary polypharmacy consultation service of the geriatric university outpatient clinic

Sufficient mobility (minimum: Wheelchair mobility)

Disqualifiers

No sufficient communication possible

Patients classified as terminally ill by the medical staff

Patients, that are incapable to give their informed consent and who do not have a legal representative

Trial design

Treatments tested in this trial

Pharmacogenomic testing of a panel of important pharmacogenes to detect genetic variants and evaluate the association between genetically predicted and measured drug metabolism
Adverse Drug Reaction detection
Falls Efficacy Scale International (FES-I)

Treatment groups

2,000 Participants

are divided into 1 treatment group

Locations

This trial has no locations

Sponsors and collaborators

RWTH Aachen University

Lead sponsor

B. Braun Foundation

Collaborator

Source ClinicalTrials.gov