Individualized Adaptive Deep Brain Stimulation in Opioid Use Disorder
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age22-75
SponsorUniversity of California, San Francisco
About this trial
The purpose of this study is to determine if personalized (adaptive) Deep Brain Stimulation (DBS) based upon invasive brain mapping is safe and can lead to better outcomes like reductions in craving and opioid use.
Eligibility criteria
Qualifiers
Adults (all genders) 22 to 75 years old.
Current diagnosis of severe primary opioid use disorder (OUD) (>= 6 on DSM-5 OUD criteria) (any form of opioid use).
History of opioid use for more than 5 years.
Participants are seeking treatment for their OUD.
Disqualifiers
Pregnancy or lactation.
Non-English speaking.
Participants are not willing to start MOUD treatment with buprenorphine or to switch MOUD to buprenorphine if they are already on other MOUD, for the duration of the study.
OUD treatment with another investigational drug or other intervention within 3 months.
Trial design
Treatments tested in this trial
- Deep Brain Stimulation
Treatment groups
6 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov