Inflammatory and Metabolic Prognostic Assessment in Critically Ill Neurological Patients
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorYan Zhang
About this trial
The study aims to develop and validate a prognostic prediction model for adverse outcomes in neurocritical patients receiving enteral nutrition based on key inflammatory and metabolic markers. This model will serve as a clinical tool to help physicians identify high-risk patients and guide individualized nutritional support strategies.
Eligibility criteria
Qualifiers
Age between 18 and 80 years, no gender restrictions.
Within 7 days of disease onset and expected NICU stay of at least 7 days.
Eligible for enrollment within 24 hours of NICU admission, with enteral nutrition (EN) initiated and continued for at least 7 days.
Non-traumatic severe brain injury patients (including cerebrovascular disease and encephalitis) with a Glasgow Coma Scale (GCS) score ≤12.
Disqualifiers
Severe malnutrition prior to admission, defined as BMI < 16 kg/m².
Pregnant or lactating women.
Receiving hypothermia treatment or core body temperature < 36°C.
End-stage disease with an expected survival time of < 48 hours, or severe dysfunction of the heart, lungs, or other vital organs, leading to hemodynamic instability.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
1,185 Participants
are grouped into 5 trial groupsSponsors and collaborators
Yan Zhang
Lead sponsor
Xuanwu Hospital, Beijing
Sponsor institution
Source ClinicalTrials.gov