Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorFrançois Lellouche

About this trial

The main objective is to evaluate the FreeO2 device combined with noninvasive respiratory support technique for COPD patients and postoperative bariatric surgery patients.

The main hypothesis is that FreeO2 device for oxygen therapy associated with NIV or nasal high flow oxygen therapy (NHFOT) allows to reach better oxygenation and avoid hypoxemia and hyperoxia.

Eligibility criteria

Qualifiers

Respiratory acidosis (pH <= 7.35 and PaCO2 > 45 mmHg), with or without NIV (last blood gas available during hospitalization)

Oxygen therapy and/or SpO2 <90% room air (FiO2 <= 50% or nasal cannula <= 7 L/min to maintain SpO2 90%)

High flow nasal cannula with flow <= 30 L/min

Patients using CPAP before the surgery (obstructive sleep apnea documented).

Disqualifiers

Age < 18

Pregnancy

Respiratory distress or other clinical situation requiring continuous NIV or CPAP

Glasgow < 12 or agitation/delirium/dementia (limiting NIV)

Trial design

Treatments tested in this trial

  • Washout period
  • NIV - FreeO2
  • Nasal High flow Oxygen therapy - FreeO2
  • CPAP - Oxygen constant flow
  • CPAP - FreeO2

Treatment groups

10 Participants
are divided into 2 treatment groups

Sponsors and collaborators

François Lellouche

Lead sponsor

Laval University

Sponsor institution