About this trial
The objective of this clinical, longitudinal, prospective, randomised (randomised) unmasked study is to analyse whether electrical and manual vagal stimulation produces changes in heart rate variability in a healthy population and it have a beneficial clinical effect in reducing dysautonomic symptoms.
The main questions it seeks to answer are:
* Will non-invasive (manual and electrical) stimulation of the vagus nerve produce a significant change in heart rate variability, generating effects on the regulation of the autonomic nervous system, increasing the activation of the parasympathetic nervous system and decreasing the activation of the sympathetic nervous system? * Will non-invasive (manual and electrical) stimulation of the vagus nerve have a beneficial clinical effect in reducing dysautonomic symptoms such as fatigue and improving sleep quality? * Will noninvasive (manual and electrical) vagus nerve stimulation improve quality of life? * Are there differences in the level of satisfaction with the treatment after the intervention program received?
Two groups of participants will be formed:
* Transcutaneous auricular vagus nerve stimulation consists of applying electrical stimulation to the auricular branch of the vagus nerve using a 2-pole stimulation electrode. Stimulation is performed for 1 hour per day for 10 days (5 days per week). * Manual vagus nerve intervention consists of applying a protocol of manual therapy techniques to the vagus nerve and along its path, during 4 sessions lasting 30 minutes, 2 interventions per week.
Eligibility criteria
Qualifiers
Healthy volunteers between 40 and 70 years of age.
No known neurological pathology.
Willingness to participate voluntarily in the study.
Disqualifiers
Cognitive impairment objectively assessed by a neurologist and considered relevant.
Contraindications for the application of transcutaneous auricular stimulation (implanted cardiac pacemaker or deep brain stimulation treatment).
Consumption of tea, caffeine, energy drinks, alcohol or tobacco in the two hours prior to the intervention.
Trial design
Treatments tested in this trial
- Electrical stimulation of the vagus nerve
- Manual stimulation of vagus nerve