Influence of the Gut Microbiome on Blueberry Polyphenol Metabolites
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorColorado State University
About this trial
The objective of this study is to determine whether inter-individual differences in the gut microbiome influence exposure to blueberry polyphenol metabolites. We will use pharmacokinetics of blueberry polyphenols after an acute blueberry exposure to group individuals into "metabotypes", groups of individuals based on similarity in their metabolite profiles. We will then use multi-omic approaches to determine whether the gut microbiome predicts an individual's metabotype.
Eligibility criteria
Qualifiers
Healthy adults ≥18 years of age
Able and willing to provide informed consent
Willing and able to adhere to all study procedures and visit requirements
Disqualifiers
Age <18 years
Pregnant or breastfeeding
Presence of chronic diseases, including but not limited to cardiovascular disease, diabetes, cancer, kidney, liver, gastrointestinal, or pancreatic disease
Use of medications for chronic diseases that may interfere with study outcomes
Trial design
Treatments tested in this trial
- Freeze-dried blueberry powder beverage
Treatment groups
125 Participants
are divided into 1 treatment groupSponsors and collaborators
Colorado State University
Lead sponsor
Florida State University
Collaborator
National Center for Complementary and Integrative Health (NCCIH)
Collaborator
University of Utah
Collaborator
King's College London
Collaborator
Source ClinicalTrials.gov