Inspiratory Muscle Training in Amiotrophyc Lateral Sclerosis
ConditionAmyotrophic Lateral Slerosis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorUniversity Ramon Llull
About this trial
Amyotrophic Lateral Sclerosis (ALS) progressively damages the nerve cells responsible for voluntary muscle movement. Over time, this leads to weakness in different muscles such as those used for movement or breathing. Breathing problems are one of the main causes of complications and reduced survival in people with ALS. This happens because the inspiratory muscles-those that help draw air into the lungs-gradually lose strength.
The study has the aim to explore the benefits of training inspiratory muscles in ALS patients in order to maintain the setrength of these muscles for as long as possible and look the impact on respiratory function.
Eligibility criteria
Qualifiers
Patients diagnosed with spinal ALS
men and women
diagnosis date less than two years ago, according to the "El Escorial" criteria (Appendix 2)
PIM above the lower limit of normal
Disqualifiers
Patients with signs of respiratory muscle weakness (MIP and MEP below the LLN and abnormal decubitus tests19-21)
Nocturnal hypoventilation
Inability to perform the measurement tests
Inability to understand and perform the exercises
Trial design
Treatments tested in this trial
- Inspiratory muscle training
- Sham training
Treatment groups
44 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov