Integrated Patient Avatars for Guiding Systemic Therapy Treatments in Metastatic Breast Cancer Patients
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSunnybrook Health Sciences Centre
About this trial
The investigators propose to use clinically validated patient avatar technology ("PDXovo") that can test multiple drugs against patients' cancers to identify the most promising systemic therapy for each individual.
Eligibility criteria
Qualifiers
Age 18+.
Metastatic breast cancer irrespective of subtype.
Measurable disease as per RECIST 1.1 criteria.
Metastatic disease involving the lymph nodes and/or visceral organs is required.
Disqualifiers
Lack of feasibility to obtain a core biopsy of a metastatic site other than the bone (e.g. a metastatic lesion cannot be safely sampled due to proximity to vasculature).
Inability to provide informed consent.
Trial design
Treatments tested in this trial
- Needle Core Biopsies
Treatment groups
No treatment groups listed
Sponsors and collaborators
Sunnybrook Health Sciences Centre
Lead sponsor
AFP Innovation Fund
Collaborator
Source ClinicalTrials.gov