Integrating Metabolic and Vascular Sensors to Monitor Cardiometabolic Disorders After Nutrition Interventions

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorVA Greater Los Angeles Healthcare System

About this trial

It is a 12-week study. The participants will follow three different diets, and during each diet period, and the participants will wear our device, and blood samples will be collected.

Eligibility criteria

Qualifiers

United States Veterans

Male or female, age 18-55 years at the time of signing informed consent.

at least 2 of the following: waist circumference > 40" for men and 35" for women, FBS >100 mg/dl, triglycerides > 150 but < 500 mg/dL, HDL < 40 mg/dL, Pre- hypertension or hypertension (BP>120/80 mmHg but <150/90 mmHg)

Disqualifiers

History of diabetes require medications

History of alcohol intake ≥ 20g/day

History of cirrhosis

Renal impairment measured as estimated Glomerular Filtration Rate (eGFR) value of <30 mL/min/1.73 m2

Trial design

Treatments tested in this trial

  • Mediterranean diet (MED), high-fat/low carb diet (HF/LC), and low-fat diet (LF)
  • The integrated sweat sensor and vascular sensor (wearable)
  • continuous glucose monitor (CGM)

Treatment groups

54 Participants
are divided into 4 treatment groups