The goal of this clinical trial is to investigate if blood glucose responses are similar between and within individuals in response to standardized exercise in adults with and without Type 1 diabetes. The main questions it aims to answer are:
What is the reproducibility of acute glycaemic responses to exercise within and between subjects in adults living with Type 1 Diabetes and in healthy adults? What is the agreement between glucose levels obtained by continuous glucose monitor (CGM) and blood glucose monitor?
Participants will cycle on a cycle ergometer or rest after consuming a standardized breakfast, while glucose levels are monitored by CGM and capillary blood sampling.
age between 18 and 60 years old;
being healthy individuals;
diagnosis of T1D for >18 months;
hypoglycaemia self awareness.
presence of cardiovascular disease or contraindications to exercise;
infectious or inflammatory conditions;
chronic renal or liver disease;
pregnancy;
University College Dublin
Lead sponsor
Taighde Éireann - Research Ireland
Collaborator
Irish Research Council
Collaborator