Interaction Between Early Trauma and Odor-induced Dopamine Release

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-30
SponsorHôpital le Vinatier

About this trial

This prospective, double-blind, parallel-group controlled trial aims to investigate the consequence of early trauma on dopamine release evoked by positive valence odors.

Eligibility criteria

Qualifiers

Aged 18 years or older

Have been selected based on the Childhood Trauma Questionnaire score

Non-smoker

Be able to speak and read French

Disqualifiers

A pre-existing condition that affects olfaction including congenital anosmia, upper respiratory tract infection, nasal and/or sinus disease,

Be on medication, with the exception of oral contraceptives

Pregnant or breast-feeding woman (check with urine pregnancy tests);

Contraindications to TMS or MRI (implanted medical devices or metallic foreign body in the head);

Trial design

Treatments tested in this trial

  • High score at Childhood Trauma Questionnaire.
  • Low score at Childhood Trauma Questionnaire.

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators