Intermediate Age-related Macular Degeneration - Multimodal Analysis and Longitudinal Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age55-95
SponsorUniversidade Nova de Lisboa

About this trial

Study: observational prospective clinical study. Study population: Subjects over 55 years old with drusen secondary to intermediate AMD.

Recruitment: at the Medical Retinal Consultation from the Ophthalmology Department of CHULC.

Primary outcome: Identifying imaging predictors of iAMD progression.

Eligibility criteria

Qualifiers

To verify the existence of drusen secondary to intermediate AMD; Soft, cuticular and reticular pseudo-drusen will be considered.

Accept and sign the consent.

Disqualifiers

Patients are excluded if it is not possible to obtain good quality CFP, SD-OCT, OCT-A images, if refractive error is ≥±6D or if there is any evidence of accumulation of extracellular fluid, haemorrhage, exudates or fibrosis.

Additional exclusion criteria included any history of retinal surgery including laser treatment, signs of diabetic retinopathy, history of retinal vascular occlusion, history of anti-VEGF treatment in the study eye or any signs or history of hereditary retinal or macular dystrophy.

Trial design

Treatments tested in this trial

  • Orthoptic assessment (Outcome measure)

Treatment groups

150 Participants
are divided into 1 treatment group

Sponsors and collaborators

Universidade Nova de Lisboa

Lead sponsor

iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, UNL

Collaborator

Centro Hospitalar de Lisboa Central

Collaborator

Centro Hospitalar De São João, E.P.E.

Collaborator