The purpose of this study is to investigate whether time-restricted feeding, a form of intermittent fasting, before surgery improves insulin resistance around the time of surgery, compared to carbohydrate drinks and standard fasting before surgery.
Undergoing elective orthopaedic surgery;
Intermediate, major or complex surgery according to the Surgical Outcome Risk Tool (SORT; http://www.sortsurgery.com/) severity of surgery classification;
Scheduled for surgery at least 17 days from the date of screening;
Motivated to follow a time restricted feeding regimen.
History of diabetes mellitus;
History of feeding or eating disorders;
History of delayed gastric emptying or gastro-oesophageal reflux
Active malignancy
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Lead sponsor
Amsterdam UMC, location AMC
Sponsor institution
European Society of Anaesthesiology and Intensive Care
Collaborator