Intermittent Versus Continuous Glucose Monitoring in Intensive Care Unit

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Medical Centre Ljubljana

About this trial

Glucose control is an important part of supportive care for critically ill patients. Achieving optimal glucose control in such situations is challenging due to frequent fluctuations in blood glucose levels. These changes are often difficult to detect because the monitoring procedures are complex and require significant staff involvement, frequent blood draws, and consequent blood loss. Continuous glucose monitoring (CGM) is a simple and minimally invasive technique that has been approved and increasingly used by people with diabetes mellitus. However, its effectiveness in terms of glucose control management and accuracy in conditions with severe organ dysfunction has not been established.

The goal of this study is to assess the performance of CGM-guided glucose control in comparison to the standard glucose monitoring procedure. Additionally, the accuracy of CGM measurements under critical conditions will be evaluated against the standard of care.

Eligibility criteria

Qualifiers

age ≥ 18 years

admission to the level 3 ICU

two consecutive blood glucose measurements > 10.0 mmol/L

intravenous insulin therapy

Disqualifiers

expected ICU stay < 48 hours

pregnancy

type 1 diabetes

diabetic emergencies (DKA, DAHS)

Trial design

Treatments tested in this trial

  • Continuous glucose monitoring
  • Control Arm - standard of care

Treatment groups

200 Participants
are divided into 2 treatment groups