International Prospective Registry on Local Treatment Approaches in MLS

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorThe Netherlands Cancer Institute

About this trial

To prospectively study commonly used local treatment approaches in Myxoid Liposarcoma (MLS)

Eligibility criteria

Qualifiers

Age > 18 years

Biopsy proven MLS, including the reciprocal chromosomal translocation t(12;16)(q13;p11)

ECOG PS 0-2

Written informed consent to share coded information in this international Registry

Disqualifiers

Prior radiotherapy to the target area

Pregnancy

Trial design

Treatments tested in this trial

  • Surgery
  • Preoperative RT 36Gy
  • Preoperative RT 50Gy
  • Postoperative RT 50-66Gy
  • RT 36Gy

Treatment groups

300 Participants
are divided into 5 treatment groups

Sponsors and collaborators

The Netherlands Cancer Institute

Lead sponsor

Radboud University Medical Center

Collaborator

Maastro Clinic, The Netherlands

Collaborator

University Medical Center Groningen

Collaborator

Leiden University Medical Center

Collaborator

Vienna General Hospital

Collaborator

M.D. Anderson Cancer Center

Collaborator

University Hospital, Antwerp

Collaborator

Universitetssykehus

Collaborator

Haukeland University Hospital

Collaborator

Universitäts-Frauenklinik Graz

Collaborator

University Hospital Heidelberg

Collaborator

Mayo Clinic

Collaborator

Aarhus University Hospital

Collaborator

National Cancer Center, Japan

Collaborator

Princess Margaret Hospital, Canada

Collaborator

MOUNT SINAI HOSPITAL

Collaborator

University of Sydney

Collaborator

Institute for Cancer Research and treatment

Collaborator

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Collaborator

Institut Curie

Collaborator

Australia and New Zealand Sarcoma Association

Collaborator