Interpretation and Optimization of Nutrition in the Intensive Care Units

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorDim3

About this trial

Despite recommendations, inadequate nutritional intake in intensive care unit (ICU) patients remains frequent and can lead to complications such as infections, increased length of stay, prolonged weaning from ventilation, increased long-term mortality, and decreased quality of life after intensive care. Studies have shown that patients only receive up to 50-60% of prescribed calories and proteins due to many factors leading to nutritional support interruptions such as ICU procedures, physical therapy, transport for imaging or invasive procedures outside the ICU, and nutrition intolerance.

Furthermore, this discrepancy between prescribed and delivered nutrition may go largely unnoticed, due to issues concerning inadequate manual or automated monitoring of delivered nutrition. A joint "Call to Action" by ASPEN, the Academy of Nutrition and Dietetics, and the American Society of Health-System Pharmacists stated that parenteral nutrition errors and their contributing factors could be prevented by improving the functionality of in-house Clinical Decision Support Systems and the interfaces between electronic health records (EHRs), automated preparation devices and pharmacy systems.

Nutrow® is a software package designed to support nutritional management based on the calculation of recommended calorie and protein requirements, real-time calculation and monitoring of calorie and protein prescriptions, real-time calculation and monitoring of calories and protein truly delivered to patients, and information feedback to prescribers. Feedim® is a Medical Device Data System (MDDS), designed by Dim3, which transmits information from enteral feeding pumps to third-party software, such as Nutrow®.

The aim of the study is to assess whether the joint use of Nutrow-Feedim improves the achievement of nutritional objectives in ICU patients prior to oral intake by reducing the discrepancy between prescribed and delivered calories and protein.

Eligibility criteria

Qualifiers

Age 18 and over.

French Social Security system registration.

First stay in ICU

Admitted to the Lille University Hospital Surgical ICU for at least 3 days.

Disqualifiers

Age under 18

Burn patient

Admitted to the ICU with a prior active enteral/parenteral nutritional support before day 3, except trophic nutrition

Dying patient, not-to-be-resuscitated order, or other treatment limitation decision at ICU admission

Trial design

Treatments tested in this trial

  • Nutritional support prescription and delivery monitoring feedback
  • Usual care

Treatment groups

144 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Dim3

Lead sponsor

Baxter Healthcare Corporation

Collaborator

University Hospital, Lille

Collaborator