Intestinal Immunity in Neurologic Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-99
SponsorYale University
About this trial
The purpose of this study is to ascertain the functional profiles of the immune cells within the gastrointestinal tract and to determine how these cells contribute to autoimmune and neurologic diseases.
Eligibility criteria
Qualifiers
Age 18 and up
Recommended to under a screening colonoscopy (+/- upper endoscopy) as part of standard of care. This includes healthy individuals as well as those with neurologic and/or autoimmune diseases. OR
Willing to undergo research colonoscopy (+/- upper endoscopy) for research
Disqualifiers
Currently pregnant. Women of childbearing potential would perform a point of care urine pregnancy test prior to colonoscopy/endoscopy.
Known or suspected, chronic inflammatory gastrointestinal disease (e.g. inflammatory bowel disease)
Known, acute or chronic infections
Systemic antibiotic (PO or IV) use within 3 months of colonoscopy
Trial design
Treatments tested in this trial
- Colon Tissue Biopsy
Treatment groups
100 Participants
are divided into 3 treatment groupsSponsors and collaborators
Yale University
Lead sponsor
National Institutes of Health (NIH)
Collaborator
Chan Zuckerberg Biohub
Collaborator
The Brain Research Foundation
Collaborator
Source ClinicalTrials.gov