Intra-Articular Dexmedetomidine: A Treatment for Chronic Knee Pain

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-75
SponsorTanta University

About this trial

Chronic knee osteoarthritis (KOA) is a painful condition with limited treatment options. Non-pharmacological approaches often fall short, leading to decreased quality of life. Ozone therapy, a simple and affordable treatment, has shown promise for pain relief. Dexmedetomidine (DEX), a sedative and analgesic, has been used successfully as an adjuvant to anesthesia and local anesthetics. Given its potential for pain management, exploring DEX as a treatment for KOA could offer a new and promising approach.

Eligibility criteria

Qualifiers

Patients were not assigned for surgical intervention;

Patients were free of

Disqualifiers

Patients were assigned for surgical intervention;

Patients who had uncontrolled hypertension and/or diabetes mellitus;

Patients who had uncompensated cardiac, renal, or hepatic diseases;

Patients with coagulopathy, spinal deformity, allergy, or contraindication for the used drugs;

Trial design

Treatments tested in this trial

  • Triamcinolone Acetonide
  • Bupivacaine Hydrochloride
  • Dexmedetomidine

Treatment groups

70 Participants
are divided into 2 treatment groups

Sponsors and collaborators