Intraarticular Injection of Botox and Hyaluronic Acid in Knee Osteoarthritis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50+
SponsorTanta University
About this trial
This study aims to compare the efficacy of intra-articular injection of Botulinum toxin and hyaluronic acid on pain in knee osteoarthritis.
Eligibility criteria
Qualifiers
Age ≥ 50 years.
Both genders.
Chronic knee osteoarthritis (KOA) according to American College of Rheumatology criteria for the diagnosis of knee osteoarthritis.
Third or fourth grade Kellgren and Lawrence system for classification of osteoarthritis based on radiological data, it is a common method of classifying the severity of osteoarthritis (OA) using five grades according to the following sites and projections.
Disqualifiers
History of intra-articular injection within the last 6 months,
History of surgery on the knee joint or major trauma to the lower limb causing fracture.
Body mass index (BMI) more than 40 kg/m2.
Medical conditions affecting the joint or lower extremity function such as severe osteoporosis, rheumatoid arthritis, collagen vascular diseases, and gout.
Trial design
Treatments tested in this trial
- Hyaluronic acid
- Botulinum toxin type A
Treatment groups
50 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov