Intralesional Cryosurgery Alone Versus Combined With 5-FU and Triamcinolone for Keloids
ConditionKeloid
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssiut University
About this trial
evaluate the efficacy and safety of intralesional cryosurgery alone compared with intralesional cryosurgery combined with intralesional 5-fluorouracil and triamcinolone acetonide in the treatment of keloids.
Eligibility criteria
Qualifiers
Adult patients (≥18 years) with clinically diagnosed keloids .
Keloids of size 1-10 cm in greatest dimension .
Keloids of at least one year duration
Disqualifiers
Females who are pregnant, planning pregnancy, or lactating .
Hypertrophic scars .
Chronic kidney or liver disease (relevant for 5-FU safety) .
Patients with active inflammation, infection, or ulcer at or around the keloid or Lesions suspicious for malignancy .
Trial design
Treatments tested in this trial
- Intralesional Cryotherapy + Saline Injection
- Intralesional Cryotherapy + TAC/5-FU Injection
Treatment groups
32 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Assiut University
Lead sponsor
Northwest Biotherapeutics
Sponsor institution
Source ClinicalTrials.gov