Investigating Hereditary Risk In Thoracic Cancers (INHERIT)
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorDana-Farber Cancer Institute
About this trial
The purpose of this research study is to learn more about the inherited risk for developing lung cancer.
Eligibility criteria
Qualifiers
Cohort 1: individuals with or with high risk of carrying an EGFR T790M or other EGFR germline variant identified in blood or saliva, including via somatic single or multi-gene panel testing (MGPT). This includes both probands and family members.
Participants with variants of uncertain significance may be eligible at the PI's discretion
Cohort 2: individuals with or with high risk of carrying non-EGFR germline variants suggestive of a potential inherited lung cancer risk, identified in blood or saliva, including via somatic single or multi-gene panel testing (MGPT). This includes both probands and family members.
Participants with variants of uncertain significance may be eligible at the PI's discretion
Disqualifiers
Individuals who decline to consent
Individuals who are unable to give consent or assent and are without a designated healthcare proxy
Trial design
Treatments tested in this trial
- Data and Specimen Collection
Treatment groups
500 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov