Investigating the Acute Effects of Increasing Alanine Exposure in Healthy Participants
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age25-70
SponsorNicolai Jacob Wewer Albrechtsen
About this trial
In this study the investigators will investigate the acute effects of increasing alanine exposure on metabolic parameters in healthy participants.
Participants will participate in one study day. After initial baseline blood samples, a three-hour intravenous infusion with glucagon will be initiated. The infusion rate will be increased every 30 minutes.
Eligibility criteria
Qualifiers
Capable of understanding the participant information and signing the consent form
Between 25 and 70 years of age at the time of screening
Body mass index (BMI) ≤ 25 kg/m2 at the time of screening
Disqualifiers
Enrolment in other research projects that might interfere with the study
Diabetes diagnosis (type 1 and 2)
Pregnancy or breastfeeding
Use of medications which, in the opinion of the investigator, may jeopardise participant's safety or compliance with the protocol
Trial design
Treatments tested in this trial
- alanine
Treatment groups
15 Participants
are divided into 1 treatment groupSponsors and collaborators
Nicolai Jacob Wewer Albrechtsen
Lead sponsor
University of Copenhagen
Sponsor institution
Source ClinicalTrials.gov