About this trial
A diet high in flavonoids is becoming more established as beneficial to human health. Recent data suggest that the regular consumption of flavanols can reduce the numbers of deaths by cardiovascular disease at a population level. The mechanisms for these reductions in deaths by cardiovascular disease are still debated and little is known about their impacts on factors affecting blood viscosity. The metabolism of flavanols is complex, with different metabolites being predominant in the blood at different time points. Therefore, in this study, we will investigate the effects of green tea, a well-known source of flavanols, on blood viscosity at different time points. This will be assessed in healthy individuals with no history of cardiovascular disease aged 65+ years old. Blood viscosity will be measured before, and 2hours and 8hours after the consumption of green tea.
Eligibility criteria
Qualifiers
Participants ages 65 years and older
Non-smoker Participants with at least 2 'good' veins for giving blood
Disqualifiers
Participants under (BMI <18.5 kg/m2) or extremely over-nourished (BMI >30 kg/m2)
Participants on prescription medication for CVD or regularly taking blood thinning drugs such as aspirin.
Participants with a history of CVD or CVD in immediate family/ high resting blood pressure
Participants with any food allergies/intolerances
Trial design
Treatments tested in this trial
- Green Tea
- Control (Hot Water)
Treatment groups
Sponsors and collaborators
University of Reading
Lead sponsor
Biotechnology and Biological Sciences Research Council
Collaborator
Royal Berkshire NHS Foundation Trust
Collaborator