Investigating the Gut Microbiome and Symptomology in IBS
ConditionIrritable Bowel Syndrome (IBS)
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-64
SponsorNottingham Trent University
About this trial
This intervention study explores whether a routine physical activity intervention can help manage or relieve symptoms of Irritable Bowel Syndrome (IBS) in adults who have been clinically diagnosed with IBS. The main questions it aims to answer is:
• Primary Outcome: Does engaging in routine physical activity reduce the severity of IBS symptoms compared to baseline levels?
Comparison Group: Researchers will compare the intervention group (receiving the 12-week physical activity program) with a control group (receiving no intervention for 12-weeks).
Participant Activities and Interventions:
* Complete a 12-week walking programme. * Visit the university on 3 occasions (baseline, week-6 and week-12) for biological sample collection and sub-maximal fitness assessments. * Complete a series of subjective health related questionnaires.
Eligibility criteria
Qualifiers
Be 18-64 years old
Have CLINCALLY DIAGNOSED IBS
Know your IBS-SUBTYPE (e.g., constipation, diarrhoea, mixed/alternating)
Disqualifiers
Pregnant or breastfeeding
Organic gastrointestinal conditions (Inflammatory Bowel Disease, Coeliac Disease, Colorectal Cancer)
On medication with known influence on gastrointestinal motility (thyroid disease, diabetes mellitus, coeliac disease and neurological disease)
Have used antibiotics in the past 3 months
Trial design
Treatments tested in this trial
- Physical Activity
Treatment groups
40 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Nottingham Trent University
Lead sponsor
Nottingham University Hospitals NHS Trust
Collaborator
University of Reading
Collaborator
Source ClinicalTrials.gov