About this trial
The goal of this study is to investigate whether a seaweed derived food additive, carrageenan, has an impact on the human gut microbiome in vivo. The primary purpose is to assess whether consumption of a carrageenan containing product for 4 weeks can alter the bacterial composition of the gut microbiome in healthy individuals and whether the addition of a prebiotic fibre, inulin, to the product has an enhanced beneficial impact of the gut composition. The main questions to answer are:
Does the consumption of a confectionary item containing carrageenan and inulin lead to a positive impact on the faecal microbial community when compared to the confectionary item containing no carrageenan and no inulin (placebo)? Participants will be asked to consume 2 gummy sweets for 4 week period and provide stool and urine samples on 3 occasions over a 9 week period.
Does the consumption of a confectionary item containing carrageenan and inulin improve gastrointestinal comfort measured using overall SHS-GI score when compared to baseline measurements recorded during run in period?
Eligibility criteria
Qualifiers
Healthy individuals
Disqualifiers
Prescribed antibiotics in the last 3 months
Individuals with any gut disorders such as IBS or IBD
individuals with any food allergies or intolerances
Individuals who regularly consume pre or probiotics
Trial design
Treatments tested in this trial
- Carrageenan gummy sweet
- Carrageenan and inulin gummy sweet
- Placebo agar agar gummy
Treatment groups
Sponsors and collaborators
University of Reading
Lead sponsor
Cargill R&D Centre Europe, Havenstraat 84, 1800 Vilvoorde, Belgium
Collaborator