Investigating the Impact of the Seaweed Derived Food Additive, Carrageenan, on the Human Gut Microbiome

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorUniversity of Reading

About this trial

The goal of this study is to investigate whether a seaweed derived food additive, carrageenan, has an impact on the human gut microbiome in vivo. The primary purpose is to assess whether consumption of a carrageenan containing product for 4 weeks can alter the bacterial composition of the gut microbiome in healthy individuals and whether the addition of a prebiotic fibre, inulin, to the product has an enhanced beneficial impact of the gut composition. The main questions to answer are:

Does the consumption of a confectionary item containing carrageenan and inulin lead to a positive impact on the faecal microbial community when compared to the confectionary item containing no carrageenan and no inulin (placebo)? Participants will be asked to consume 2 gummy sweets for 4 week period and provide stool and urine samples on 3 occasions over a 9 week period.

Does the consumption of a confectionary item containing carrageenan and inulin improve gastrointestinal comfort measured using overall SHS-GI score when compared to baseline measurements recorded during run in period?

Eligibility criteria

Qualifiers

Healthy individuals

Disqualifiers

Prescribed antibiotics in the last 3 months

Individuals with any gut disorders such as IBS or IBD

individuals with any food allergies or intolerances

Individuals who regularly consume pre or probiotics

Trial design

Treatments tested in this trial

  • Carrageenan gummy sweet
  • Carrageenan and inulin gummy sweet
  • Placebo agar agar gummy

Treatment groups

99 Participants
are divided into 3 treatment groups

Sponsors and collaborators

University of Reading

Lead sponsor

Cargill R&D Centre Europe, Havenstraat 84, 1800 Vilvoorde, Belgium

Collaborator