About this trial
This study aims to investigate the presence of central sensitization and its associated parameters in patients with lipedema. Lipedema is a chronic and hereditary condition that primarily affects the lower extremities in women and is often associated with hormonal changes. Symptoms such as pain, swelling, and tenderness are common in lipedema, and these symptoms may be related to central sensitization. Additionally, the ultrasonographic findings and pain sensitivity in lipedema will be compared with those of healthy individuals. This study seeks to contribute to the diagnosis and treatment process of lipedema.
Eligibility criteria
Qualifiers
Lipedema; Diagnosis of lipedema Aged between 18 and 65 years Literate Willing to participate in the study
control group; Being completely healthy (no internal/metabolic issues such as diabetes, obesity, or hypothyroidism, and no diagnosis of lipedema) BMI ≤ 30 Aged between 18 and 65 years Literate Willing to participate in the study
Disqualifiers
Lipedema group; Under 18 or over 65 years of age Presence of concurrent lymphedema, chronic venous insufficiency, deep vein thrombosis, polyneuropathy, or fibromyalgia Illiterate Not willing to participate in the study
Control group; Under 18 or over 65 years of age Presence of concurrent lymphedema, chronic venous insufficiency, deep vein thrombosis, polyneuropathy, fibromyalgia, systemic rheumatic diseases, active cancer, infections, or pregnancy Illiterate Not willing to participate in the study
Trial design
Treatments tested in this trial
- Pain-Pressure Threshold Measurement With an Algometer
- Central Sensitization Inventory
- Numeric Rating Scale
- Lower Extremity Functional Scale
- Short form 12
- lower extremity volumetric measurement
- lower extremity circumference measurement
- Bioelectrical Impedance Analysis
- Ultrasound