Investigation of the Effects of Sleep Fragmentation on Itch and Pain Sensitivity
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorAalborg University
About this trial
In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep fragmentation on itch:
* To investigate similarity and differences between itch and pain by comparing the effect of sleep deprivation in them. * To evaluate the inflammatory state induced by sleep fragmentation via the analysis of C-reactive protein (CRP) levels from blood samples. * To correlate the anxiety and depression scores (evaluated through questionnaires) with itch and pain sensitivity and evaluate how they are affected by sleep fragmentation.
Eligibility criteria
Qualifiers
Healthy men and women
18-60 years
Speak and understand English
Access to a smartphone during the experimental nights
Disqualifiers
Pregnancy or lactation
Drug addiction defined as any use of cannabis, opioids, or other drugs
Previous or current history of neurological, dermatological, immunological musculoskeletal, cardiac disorder or mental illnesses (psychiatric diagnosis) that may affect the results (e.g., neuropathy, muscular pain in the upper extremities, anxiety, depression, schizophrenia etc.)
Moles, wounds, scars, or tattoos in the area to be treated or tested
Trial design
Treatments tested in this trial
- Histamine
- Cowhage
Treatment groups
30 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov