iPACK Block vs. Periarticular Infiltration for TKA Pain Control

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorTurgutlu State Hospital

About this trial

This study aims to retrospectively compare two different multimodal analgesic techniques for pain management after total knee arthroplasty (TKA). The primary purpose is to evaluate whether a combination of two specific nerve blocks administered by an anesthesiologist (Femoral Triangle Block + iPACK block) resulted in superior postoperative pain control compared to a hybrid combination of a nerve block and a local infiltration administered by the surgeon (FTB + Periarticular Infiltration \[PAI\]).

The hypothesis is that the FTB + iPACK combination is associated with a significant reduction in Numeric Rating Scale (NRS) pain scores with movement at 24 hours postoperatively. This is a retrospective, observational cohort study conducted at a single center, involving medical records of patients who underwent primary unilateral TKA. Data from patients who received either FTB + iPACK or FTB + PAI as part of their standard clinical care will be extracted and analyzed retrospectively.

Eligibility criteria

Qualifiers

American Society of Anesthesiologists (ASA) physical status II-III.

Scheduled for elective, primary, unilateral total knee arthroplasty for osteoarthritis.

Able to provide written informed consent.

Disqualifiers

Patient refusal to participate or contraindication to regional anesthesia.

Known allergy to any study medications (local anesthetics, NSAIDs, tramadol, morphine, paracetamol).

History of chronic opioid use (defined as daily use for >3 months)

Pre-existing peripheral neuropathy in the operative limb.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

100 Participants
are grouped into 2 trial groups

Sponsors and collaborators