Ischemic Preconditioning Reduces the Severity of Acute Kidney Injury After Partial Nephrectomy
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorSun Yat-sen University
About this trial
It is demonstrated that remote ischemic preconditioning can alleviate the degree of acute renal injury on the operated side in patients undergoing partial nephrectomy.
Eligibility criteria
Qualifiers
Patients who are scheduled to undergo partial nephrectomy, with no specific surgical procedure limitation, including laparoscopic surgery, robot-assisted surgery, and open surgery
Aged 18 to 80
Possess good organ function status: sufficient organ function (based on the normal values of the clinical trial center)
Blood routine test: WBC≥3.5×10^9/L, absolute neutrophil count ≥1.5×10^9/L, PLT≥75.0×10^9/L, HGB≥80g/L;
Disqualifiers
The anesthesiologist assesses that the patient cannot tolerate general anesthesia surgery
Individuals with severe cardiovascular and cerebrovascular diseases, uncontrolled hypertension, and diabetes
Estimated glomerular filtration rate (eGFR) < 30 ml/min/1.73m²
Horseshoe kidney
Trial design
Treatments tested in this trial
- Ischemic preconditioning
- NO ischemic preconditioning
Treatment groups
174 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov