Isokinetic Training With Blood Flow Restriction for Patellofemoral Pain Syndrome

ConditionPatellofemoral Pain Syndrome

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-40

SponsorNanjing Mingzhou Rehabilitation Hospital

About this trial

This randomized controlled trial aims to investigate the effects of isokinetic training combined with blood flow restriction (BFR) in individuals with patellofemoral pain syndrome (PFPS).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Participants aged 18 to 40 years.

Clinical diagnosis of patellofemoral pain syndrome (PFPS).

Presence of anterior or retropatellar knee pain for at least 3 months.

Pain provoked by at least two activities that increase patellofemoral joint load, including squatting, stair climbing, running, jumping, prolonged sitting, or kneeling.

Disqualifiers

History of knee surgery or significant trauma to the lower extremity within the previous 12 months.

Clinical evidence of other knee disorders, including ligament injury, meniscal injury, patellar instability, osteoarthritis, or tendinopathy.

Presence of neurological, cardiovascular, or systemic musculoskeletal disorders that may affect lower limb function or exercise participation.

Current participation in other structured lower extremity rehabilitation or strength training programs.

Trial design

Design model

Parallel

Treatments tested in this trial

Isokinetic Training
Device
Participants in this group will receive supervised isokinetic muscle strength training targeting the knee musculature using an isokinetic dynamometer. Each session will last 30 minutes throughout the intervention period.
Isokinetic Training Combined With Blood Flow Restriction
Device
Participants in this group will receive isokinetic muscle strength training combined with blood flow restriction (BFR). BFR will be applied to the proximal thigh using a pneumatic cuff at an individualized pressure based on limb occlusion pressure. Isokinetic training will target the knee musculature using an isokinetic dynamometer under supervised conditions. Each session will last 30 minutes, with training performed multiple times per week throughout the intervention period.
Aerobic Cycling Exercise
Device
Participants in this group will receive supervised aerobic cycling exercise using a stationary bicycle. Training will be performed at a moderate intensity for 30 minutes per session throughout the intervention period.

Treatment groups

60 Participants

are divided into 3 treatment groups

Group A: IT+BFR groupExperimental treatment 1 intervention

Group B: IT groupActive comparator 1 intervention

Group C: ACE groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

Anterior Knee Pain Scale (AKPS)

The AKPS is a validated questionnaire used to assess pain and functional limitations associated with patellofemoral pain syndrome. Scores range from 0 to 100, with higher scores indicating better knee function and fewer symptoms.

Time frame

From enrollment to the end of treatment at 4 weeks

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Nanjing Mingzhou Rehabilitation Hospital

Lead sponsor

Guilin institute of information technology

Collaborator

Source ClinicalTrials.gov

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