Isolation of Human Recombinant Therapeutic Monoclonal Anti-Pseudomonas Antibodies

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Grenoble

About this trial

Pseudomonas aeruginosa is a pathogenic bacteria for human, especially in hospital settings. It can sometimes be multi-resistant to many or even to all antibiotics usually used for its treatment.

The aim of the study is to isolate and produce therapeutic antibodies against the bacteria Pseudomonas aeruginosa in order to provide an alternative treatment to antibiotics in case of infection with an antibiotic-resistant strain of Pseudomonas aeruginosa.

Eligibility criteria

Qualifiers

Patient selected in the retrospective part of the study (patient with serum containing functional anti-Pseudomonas aeruginosa antibodies)

Patient with weight ≥ 32kg.

With a follow-up visit at Grenoble University Hospital with a blood sampling for its care

Having given its written no objection to participate in the prospective phase of this project

Disqualifiers

Legally protected patient (minor, pregnant or nursing woman, ward or ward curated, hospitalized under duress or deprived of liberty)

Trial design

Treatments tested in this trial

  • Isolation of anti-Pseudomonas antibodies from type B lymphocytes

Treatment groups

No treatment groups listed

Sponsors and collaborators