iTBS in MCI and Mild AD

ConditionsMild Cognitive Impairment (MCI)Mild Alzheimer Disease

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age50-85

SponsorNational Defense Medical Center, Taiwan

About this trial

This study aims to examine the effects of iTBS on cognitive function in individuals with MCI or mild AD, with a secondary objective of exploring prefrontal TBS mechanisms for cognitive function and the effect of iTBS on BDNF.

Eligibility criteria

Qualifiers

Clinical diagnosis of MCI (overall Clinical Dementia Rating of 0.5)

Clinical diagnosis of mild Alzheimer's Disease (overall Clinical Dementia Rating of 0.5 or 1)

Disqualifiers

History of stroke

History of uncontrol seizure

History of significant head trauma followed by persistent neurologic deficit or known structural brain abnormality

Mental illness

Trial design

Treatments tested in this trial

Active rTMS
Sham rTMS

Treatment groups

80 Participants

are divided into 2 treatment groups

Sponsors and collaborators

National Defense Medical Center, Taiwan

Lead sponsor

Source ClinicalTrials.gov