Itch Sensation Induced by Multiple Applications of Pruritogens (temporal Summation)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorAalborg University

About this trial

In This experiment, the investigators would like to design a new itch model based on the temporal summation of pruritic stimuli. The hypothesis behind this study (temporal summation) is that two overlapped applications of pruritogens will result in a higher itch sensation compared with a single application.

Eligibility criteria

Qualifiers

Healthy men and women

18-60 years

Speak and understand Englis

Disqualifiers

Pregnancy or lactation

Drug addiction defined as any use of cannabis, opioids, or other addictive drugs

Previous or current history of neurological (e.g. neuropathy), immunological (e.g. asthma, immune deficiencies, arthritis), musculoskeletal (e.g. muscular pain in the upper extremities,), cardiac disorder, or mental illnesses that may affect the results

Lack of ability to cooperate

Trial design

Treatments tested in this trial

  • Histamine
  • Cowhage

Treatment groups

26 Participants
are divided into 2 treatment groups

Sponsors and collaborators