This study is a multi-site clinical trial designed to evaluate how the body absorbs and processes Kaempferol, a naturally occurring compound found in many plant-based foods. The primary purpose of the study is to measure the pharmacokinetics and biological absorption of Kaempferol in healthy adults.
Participants will receive Kaempferol and undergo scheduled blood and urine collections over a short study period. These samples will be used to measure Kaempferol levels in the body and to assess safety and tolerability. In addition, selected biological samples will be analyzed to explore molecular changes associated with Kaempferol exposure using advanced laboratory methods.
The study will be conducted at multiple research centers in the United States using a standardized protocol to ensure consistency across sites. The information collected will help improve understanding of how Kaempferol is absorbed and metabolized in humans and will support future research and regulatory evaluation.
Healthy volunteers as determined by medical history and screening assessment
Ability to understand the study procedures and provide informed consent
Willingness and ability to comply with all study procedures, including dietary restrictions, clinic visits, blood draws, urine collection, and follow-up assessments
Willingness to abstain from restricted foods, beverages, and supplements as specified in the study protocol during the study period
Known allergy or hypersensitivity to Kaempferol or related flavonoids
Pregnancy or breastfeeding
Active or chronic infections
Cancer
University of Pittsburgh
Lead sponsor
Otsuka Pharmaceutical Co., Ltd.
Collaborator