Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAin Shams University
About this trial
This randomized, double-blind, controlled clinical trial investigates the efficacy of a sub-anesthetic dose of ketamine (0.5 mg/kg IV) in preventing post-spinal hypotension in patients undergoing elective orthopedic surgeries under spinal anesthesia. The study compares ketamine with placebo (normal saline) in terms of blood pressure stability and incidence of hypotensive episodes following spinal anesthesia.
Eligibility criteria
Qualifiers
Patients American Society of Anesthesiologists Physical Status (ASA) I to II undergoing orthopedic surgeries under spinal anesthesia.
Both Sexes.
Patients aged equal to or above 18 years.
Body mass index <35 kg/m2
Disqualifiers
Patients' refusal of procedure or participation in the study.
Patients with contraindication to spinal anesthesia.
Patients with cardiovascular or pulmonary disease.
Patients with pre-procedural hypotension (systolic arterial pressure less than 90 mmHg and/or mean arterial pressure less than 60 mmHg).
Trial design
Treatments tested in this trial
- Ketamine
- Normal Saline
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov