Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19-60
SponsorMansoura University

About this trial

Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries. From the previous documented effectiveness and safety of intravenous (IV) administration of ketorolac in the circulatory-isolated limb as a part of intravenous regional anesthesia; we hypothesized that in orthopedic surgeries done with tourniquet, intravenous (IV) administration of ketorolac after tourniquet inflation, will act as intravenous regional analgesia. So, it will prolong the postoperative analgesic duration as a primary outcome.

Eligibility criteria

Qualifiers

American Society of Anesthesiologists physical status I or II

Elective unilateral lower limb orthopedic surgery with tourniquet under spinal anesthesia

Disqualifiers

Pregnant females

Body mass index ≥ 35 kg/m2

Allergy to ketorolac

Had renal, asthmatic, vascular (Raynaud's syndrome) disease, hematological anemias

Trial design

Treatments tested in this trial

  • Ketorolac
  • Control

Treatment groups

76 Participants
are divided into 2 treatment groups

Sponsors and collaborators