Kidney Transplant Improvement Through New Exercise Training to Increase Capacity

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60+
SponsorUniversity of Pennsylvania

About this trial

The goal of this clinical trial is to learn if a home-based exercise program can be safely and feasibly used to improve physical activity and physical function in adults waiting for a kidney transplant. The study will also learn how acceptable and useful this program is for participants.

The main questions it aims to answer are:

* Can a remote exercise program be delivered successfully to people on the kidney transplant waiting list? * Do participants follow the exercise program and wear a physical activity tracker as asked? * Is the program safe and well tolerated?

Researchers will compare two groups to see if the exercise program leads to higher physical activity and better physical function:

* Usual pre-transplant care with a physical activity tracker * Usual pre-transplant care plus an online exercise program

Participants will:

* Wear a wrist activity tracker to measure daily physical activity * Complete a one-week baseline period before being assigned to a study group * Be randomly assigned (like flipping a coin) to one of two groups * If assigned to the exercise group, take part in online exercise classes at home for 12 weeks with reminders and feedback, and then another 12 weeks without reminders and feedback * Answer questionnaires about their health, activity, and experience in the study

This study may help researchers learn how to better support people waiting for kidney transplant through safe, home-based exercise programs.

Eligibility criteria

Qualifiers

be at least 60 years old

receive transplant care at Penn Medicine

be on the kidney transplant waiting list

speak and comprehend English

Disqualifiers

Have had a myocardial infarction or a stroke in the 3 months immediately prior to enrollment

Be unable to self-monitor with study devices (i.e., have a condition such as dementia)

Not cleared by PARQ or receive written medical clearance to exercise

Participate in another physical activity study

Trial design

Treatments tested in this trial

  • Exercise Rehabilitation Program with Physical Activity Tracker
  • Active control

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Pennsylvania

Lead sponsor

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborator