Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age7+
SponsorCity of Hope Medical Center

About this trial

This study evaluates the factors that contribute to chronic graft-versus-host disease, which is a complication that can occur after allogeneic hematopoietic cell transplantation.

Eligibility criteria

Qualifiers

Documented written informed consent of the participant and/or parent/guardian.

Assent from pediatric participants will be documented per institutional policies and practice.

Patients who have received allogeneic hematopoietic cell transplant (HCT) regardless of donor type, condition regimen, or GVHD prophylaxis.

Age: ≥ 18 years or ≥ 7 years if 30 kg and above

Disqualifiers

* Women of childbearing potential: Pregnant/nursing

Individuals with impaired decision-making capacity

An employee who is under the direct/ indirect supervision of the PI/ a co-investigator/ the study manager

A direct study team member

Trial design

Treatments tested in this trial

  • Non-Interventional Study

Treatment groups

75 Participants
are divided into 2 treatment groups

Sponsors and collaborators

City of Hope Medical Center

Lead sponsor

National Cancer Institute (NCI)

Collaborator