About this trial
Ischemic cerebrovascular disease will cause serious harm to the life and safety of patients, and the treatment prognosis is poor. Numerous clinical trials have demonstrated that probiotics can improve cognitive function in people under multimodal. We have previously found that Lactobacillus acidophilus administration could improve cognitive impairment in MCAO and BCAS mice. Therefore, Based on the above research background and the basis of previous studies, we believe that the administration of Lactobacillus acidophilus solid drink (pure Lactobacillus acidophilus strain) can improve the cognitive function of patients with cerebral ischemia through the "brain-gut axis".
Eligibility criteria
Qualifiers
35-60 years old;
Diagnosed as ischemic cerebrovascular disease, mild to moderate symptoms, can independently complete the neuropsychological test;
No previous operation history;
The modified Rankin scale score was 0 or 1;
Disqualifiers
Previous dementia;
hearing or visual impairment;
drugs that may or are known to affect cognitive abuse;
alcohol addiction;
Trial design
Treatments tested in this trial
- Lactobacillus acidophilus
Treatment groups
Locations
Sponsors and collaborators
Huaqiu Zhang
Lead sponsor
Tongji Hospital
Sponsor institution