Laser Outcomes Associated With (Holmium Laser Enucleation of the Prostate) HoLEP Procedures

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18-89
SponsorNorthwestern University

About this trial

The primary aim is to assess the impact of laser setting frequency and wattage during holmium laser enucleation of the prostate. There is currently no gold-standard laser settings for HoLEP procedures. In the investigator's current high-volume practice, the following settings for enucleation are: 2j 50hz. These settings are conventional settings, but there is no literature to prove optimal laser settings. The investigators hypothesizes that utilization of higher laser settings may be associated with a clinically significant (defined as \> 10%) decrease in procedural time without any detrimental postoperative outcomes, and a utilization of lower laser settings may be associated with a clinically significant (defined as \>10%) reduction in postoperative irritative voiding symptoms without any detrimental postoperative outcomes.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Males 18-89 who are undergoing HoLEP for the treatment of bothersome lower urinary tract symptoms, that are typically caused by enlarged prostates

Disqualifiers

Prostates measurements over 200g

Patients who lack decisional capacity

Patients who are non-english speakers

Trial design

Design model

Single group

Treatments tested in this trial

  • HoLEP

    Procedure/Surgery

    Patients will be randomized to one of the laser energy groups day of surgery.

Treatment groups

300 Participants
are divided into 3 treatment groups
Group A: 2J 40hz Laser EnergyExperimental treatment 1 intervention
Group B: 2J 50hz Laser EnergyExperimental treatment 1 intervention
Group C: 2J 60hz Laser EnergyExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Identifying Outcomes of 40 hz, 50 hz and 60 hz laser setting groups during Holmium Laser Enucleation of the Prostate.

Comparing operative outcomes between the 40 hz, 50 hz and 60 hz laser setting groups.

Time frame
2 years

Secondary outcomes

Other outcomes

Sponsors and contacts

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