Left Atrial Appendage Arrhythmogenic and Thrombogenic Substrate

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Hospital Bispebjerg and Frederiksberg

About this trial

The purpose of the project is to elucidate whether it is possible to identify which patients are at risk of forming blood clots that can cause stroke based on analysis of the electrocardiogram.

In connection with the operation, the small pouch known as the auricle of the heart is closed, which can be completely removed after closing. This procedure is common in patients with atrial fibrillation to protect the brain from stroke. In the project, all patients will have this auricle closed if they agree to participate in the project.

After closure, the auricle is usually discarded. We will analyze the blood and the auricle tissue taken (if available) in connection with the operation itself, together with the analysis of the electrocardiogram recorded before the planned heart operation.

Eligibility criteria

Qualifiers

signed informed consent AND

CABG

valve repair or replacement

aorta surgery

Disqualifiers

current endocarditis

follow-up not possible

Trial design

Treatments tested in this trial

  • left atrial appendage closure

Treatment groups

1,000 Participants
are divided into 1 treatment group

Sponsors and collaborators

University Hospital Bispebjerg and Frederiksberg

Lead sponsor

Rigshospitalet, Denmark

Collaborator

University of Copenhagen

Collaborator