About this trial
Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse remodeling of the left ventricle (LV) in the postoperative period. It is suggested that functional mitral regurgitation (MR) provides supra-physiological left ventricle volume overload and this fact plays positive role in early-stage post-operative left ventricle volume and function recovery. LV volume, systolic and diastolic function will be monitored with echocardiography (EchoCG) along with life quality in patients with different grades of functional mitral regurgitation secondary to severe chronic aortic insufficiency after surgical treatment of aortic regurgitation.
Eligibility criteria
Qualifiers
Age over 18 years
Planned primary elective surgery for chronic aortic regurgitation
Presence of functional mitral regurgitation
End-diastolic volume of the left ventricle >= 250 ml
Disqualifiers
Infectious endocarditis
History of myocardial infarction
Indications on simultaneous myocardial revascularisation
Acute aortic regurgitation of any etiology
Trial design
Treatments tested in this trial
- Not applicable - observational study
Treatment groups
Sponsors and collaborators
Petrovsky National Research Centre of Surgery
Lead sponsor
Voronezh regional clinical hospital #1
Collaborator