Leprosy Active Searching Trial in Brazil

ConditionLeprosy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorHospital Alemão Oswaldo Cruz

About this trial

The goal of this clinical trial is to assess whether a multifactorial active case-finding strategy improves the detection of leprosy cases in Brazil compared to usual screening practices. The main questions it aims to answer are:

\- Does the intervention increase the number of new leprosy cases detected compared to standard care?

Participants will:

* Receive community awareness about leprosy. * Be screened using the Leprosy Suspicion Questionnaire at priority areas identified by georeference tools. * Undergo clinical evaluation by a trained medical team. * If leprosy is diagnosed, affected patients will collect complementary laboratory exams

Healthcare professionals from primary care units will receive training in leprosy, while researchers will monitor changes in leprosy incidence over a 12-month period using data from Brazil's national notification system. The study will provide insights into underdiagnosis and the clinical profiles of patients who have been diagnosed.

Eligibility criteria

Qualifiers

Municipality recognized by the Brazilian Institute of Geography and Statistics as part of the Brazilian Federation.

Municipality with operational epidemiological classification by the Ministry of Health (BMoH) as: 'municipalities with cases in the period from 2015 to 2019'.

Municipality with authorization/consent from the government to participate in the study.

Disqualifiers

Municipality with extreme population size (municipalities with a number of inhabitants lower than the 10th percentile and higher than the 90th percentile).

Municipality with operational epidemiological classification by the BMoH as: 'municipalities without cases in the period 2015 to 2019'.

Municipalities with active or recent participation (less than one year) in other active-finding strategies, in addition to the usual ones: ministerial, Non-Governmental Organizations (NGOs), academic, among others.

UBS with limited multidisciplinary team (absence of physicians, nurse and/or community health agents).

Trial design

Treatments tested in this trial

  • Implementing active-case finding strategies

Treatment groups

1,925 Participants
are divided into 2 treatment groups

Sponsors and collaborators