Leptospirosis Registry - LeptoScope

ConditionLeptospirosis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorUniversity of Cologne

About this trial

Leptospirosis is a worldwide zoonotic diseases caused by pathogenic Leptospira spp. Human are accidental hosts, who acquired infections after exposition to animal urine, contaminated water or soil, infected tissue. Incidence of invasive leptospirosis disease causing acute kidney injury, acute respiratory distress syndrome (ARDS), myocarditis, hepatic dysfunction, hemorrhage and multi-organ failure, is globally increasing and there have been frequent outbreak situation throughout the world. Due to increasing outbreak situations and globally chances in species distributions, a worldwide surveillance in epidemiology and species distribution is urgently needed. The objective of the Leptospirosis Registry - LeptoScope is to overcome the lack knowledge on epidemiology, clinical course, prognostic factors and molecular characteristics for invasive leptospirosis disease.

Eligibility criteria

Qualifiers

Cultural, serological, molecular or histological evidence of invasive leptospirosis diseases

Clinical signs of disseminated leptospirosis disease without cultural, serological, molecular or histological evidence

Case controls: Matching procedures for controls: Particularly, case controls will be included at the same hospitals that conduced cases based on matching of demographics, underlying diseases and duration of hospitalization (i.e. one control per case, both in the same hospital).

Disqualifiers

Colonization or other non-invasive infection

Cultural, serological, molecular or histological evidence without dissemination

Trial design

Treatments tested in this trial

  • Retrospective data collection of demographics
  • Retrospective data collection of underlying diseases
  • Retrospective data collection of duration of hospitalization

Treatment groups

200 Participants
are divided into 2 treatment groups

Sponsors and collaborators