Lesion Formation With Pulsed Field Versus Cryobaloon Ablation as Assessed by Cardiac Magnetic Resoncance

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorHospital Clinic of Barcelona

About this trial

This randomised study will compare pulsed field ablation and cryoballoon ablation with respect to ablation lesion quality as assessed by late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) at 3 months post-ablation. Patients scheduled for first-time AF ablation will be randomised in a 2:1 fashion to receive PVI-only, either by pulsed field ablation (Farapulse Pulsed Field Ablation System, Boston Scientific) or cryoballoon ablation (Medtronic Cryoballoon Ablation System).

Eligibility criteria

Qualifiers

Patients scheduled for first-time atrial fibrillation catheter ablation

Disqualifiers

age <18 years

long-standing persistent atrial fibrillation

prior left atrial ablation

pregnancy or lactation

Trial design

Treatments tested in this trial

  • Pulmonary vein isolation

Treatment groups

104 Participants
are divided into 2 treatment groups

Sponsors and collaborators