This is a single randomised controlled trial. The investigators plan to randomise 800 participants to the levofloxacin plus metronidazole suppositories versus levofloxacin co-administered with metronidazole tablets for the treatment of chronic endometritis in a 1:1 rate. Primary outcome will be the live birth rate after the embryo transfer.
Infertile patients aged 20-42 years
Hysteroscopy and endometrial biopsy were performed, and the
Pathological diagnosis was chronic endometritis
Serum FSH level on the second day of menstruation was ≤12U/L
Patients with the following diagnoses: submucosal myoma; Uterine malformation or previous surgery for correction of uterine deformity; Intrauterine adhesions; The previous history of pelvic tuberculosis or endometrial tuberculosis or the current pathology suggested endometrial tuberculosis; Endometrial hyperplasia or endometrial cancer
Patients with spouse, previous fetal or child chromosomal abnormalities who plan to undergo preimplantation genetic screening
Patients with a history of allergy to study drugs