Lifestyle Interventions to Prevent cOgnitive Deficits in Subjects With Depressive Symptoms: From mEchanisms to Clinical pRactice

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-80
SponsorNational Science and Technology Council, Taiwan

About this trial

POWER project is a randomized, controlled, non-profit study with the primary objective of testing the effectiveness of non-pharmacological interventions-such as physical activity, cognitive training, and dietary supplementation-in reducing depressive symptoms and preventing or delaying cognitive impairments that frequently co-occur in individuals with Major Depressive Disorder (MDD).

Eligibility criteria

Qualifiers

Aged 50-80 years old

Major Depressive Disorder

Absence or mild cognitive impairment

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Soybean oil (Standard treatment)
  • Eicosapentaenoic acid (omega-3 fatty acid)

Treatment groups

120 Participants
are divided into 2 treatment groups

Sponsors and collaborators

National Science and Technology Council, Taiwan

Lead sponsor

IRCCS Centro San Giovanni di Dio Fatebenefratelli

Collaborator

University College Cork

Collaborator