About this trial
The primary objective of the Master@Heart Trial is to investigate whether lifelong endurance exercise reduces the incidence of non-calcified plaques (both mixed and soft plaques) as compared to late-onset endurance exercise and a non-athletic lifestyle.
Eligibility criteria
Qualifiers
Initiation of endurance sports before the age of 30 years
Activities at regional, national or international level
Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing
Aged 45-70 years
Disqualifiers
history of smoking (> 5 pack years)
history of diabetes
diagnosis of cardiopulmonary disorder prior to inclusion
medical treatment for arterial hypertension or hypercholesterolemia
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
Universitaire Ziekenhuizen KU Leuven
Lead sponsor
University Hospital, Antwerp
Collaborator
Jessa Hospital
Collaborator